IL18R1 Protein Product Information

Synonym : IL18R1
Protein Construction: 
A DNA sequence encoding the cynomolgus IL18R1 (F7H8F9) (Met1-Lys315) was expressed with the Fc region of human IgG1 at the C-terminus.
Source: Cynomolgus
Expression Host: Human Cells
IL18R1 Protein QC Testing

Purity: > 95 % as determined by SDS-PAGE SDS-PAGE:

IL18R1 protein
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Ala 19
Molecular Mass: 
The recombinant cynomolgus IL18R1 comprises 538 amino acids and has a calculated molecular mass of 61.1 KDa.The apparent molecular mass of the protein is approximately 70-92 KDa in SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
IL18R1 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IL18R1 Protein Description

The interleukin-18 receptor 1 (IL18R1), also known as CDw218a (cluster of differentiation w218a), is a cytokine receptor that belongs to the interleukin 1 receptor family, and a single-pass type I membrane protein contining three Ig-ike C2-type domains within the ECD. It specifically binds interleukin 18 (IL18) and is essential for IL18 mediated signal transduction, and it is reported that binding to the agonist leads to the activation of NF-kappa-B. IL-18 receptor was first described in 1989. It induces synthesis and release of IFN-gamma, IL- 8, 4 and 13, TNF-alpha and granulocyte/macrophage colony stimulating factor (GM-CSF). It modulates the function of many immunocompetent cells including macrophages, monocytes, lymphocytes and granulocytes. Another feature of IL-18 receptor is its ability to induce apoptosis of many cell types by inducing Fas ligand and receptor, aas well as granzymes. High level of IL18R1 expression is detected in Hodgkin's disease cell lines.

規(guī)格：100ug

關(guān) 鍵 詞：Cynomolgus IL18R1 Protein,技術(shù)資料,廠家現(xiàn)貨，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家

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