EWI-F / PTGFRN蛋白產(chǎn)品信息
別名: PTGFRN
表達(dá)方式:
A DNA sequence encoding the cynomolgus PTGFRN (H9ERH4) (Met1-Lys830) was expressed with a polyhistidine tag at the C-terminus.
種屬: Cynomolgus
表達(dá)宿主: Human Cells
EWI-F / PTGFRN Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Val 26
分子量:
The recombinant cynomolgus PTGFRN comprises 816 amino acids and has a calculated molecular mass of 91.5 KDa. The apparent molecular mass of it is approximately 96-106 KDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
EWI-F / PTGFRN Protein Usage Guide
儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
EWI-F / PTGFRN蛋白背景綜述
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT (n=55). EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. EWI-F expression positively correlates with the metastatic status of hLT, and that the upregulation of EWI-F expression could be one of the mechanisms underlying the loss of CD9 in solid tumours.
參考文獻(xiàn)
Stipp C S. et al., 2001, J Biol Chem. 276 (7): 4853-62.
Charrin S. et al., 2001, J Biol Chem. 276 (17): 14329-37.
Orlicky DJ. et al., 1996, Hum Genet. 97 (5): 655-8.
規(guī)格：20ug
關(guān) 鍵 詞：Cynomolgus EWI-F / PTGFRN Protein，技術(shù)資料，廠家現(xiàn)貨，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家
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