CDH13 / Cadherin-13 / H Cadherin蛋白產(chǎn)品信息
別名: CDH13
表達(dá)方式:
A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with the Fc region of human IgG1 at the C-terminus.
種屬: Rat
表達(dá)宿主: Human Cells
CDH13 / Cadherin-13 / H Cadherin Protein QC Testing
純度: (53+40.8) % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Ala 22
分子量:
The recombinant rat CDH13/Fc is a disulfide-linked homodimer. The reduced monomer comprises 912 amino acids and has a predicted molecular mass of 100.5 kDa. The apparent molecular mass of the protein is approximately 102 and 52 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
CDH13 / Cadherin-13 / H Cadherin Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CDH13 / Cadherin-13 / H Cadherin蛋白背景綜述
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.
參考文獻(xiàn)
Hart AB. et al., 2012, PLoS One. 7 (8): e42646.
Xu J. et al., 2012, BMC Cancer. 12: 243.
Jo J. et al., 2012, Obesity (Silver Spring). 20 (8): 1683-7.
規(guī)格;50ug
關(guān) 鍵 詞:Rat CDH13 / Cadherin-13 / H Cadherin Protein,現(xiàn)貨促銷,廠家,實(shí)驗(yàn)室耗材,生化試劑,上海創(chuàng)賽,博飛美科,實(shí)驗(yàn)儀器,廠家
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