COL5A2蛋白產(chǎn)品信息
別名: COL5A2
表達(dá)方式:
A DNA sequence encoding the human COL5A2(P05997) (Met1-Leu1229) was fused with Fc region of mouse IgG at the C-terminus.
種屬: Human
表達(dá)宿主: Human Cells
COL5A2 Protein QC Testing
純度: (26.7+59.2)% as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Gln 27
分子量:
The recombinant human COL5A2/mFc is a disulfide-linked homodimer. The reduced monomer comprises 1437 amino acids and has a predicted molecular mass of 138.6 kDa. The apparent molecular mass of the protein is approximately 75 and 60 in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
COL5A2 Protein Usage Guide
儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
COL5A2蛋白背景綜述
COL5A2 is a component of type V collagen. It is known as the pro-alpha2(V) chain. COL5A2, together with two pro-alpha1(V) chains can form type V procollagen. These triple-stranded, rope-like procollagen molecules arrange themselves into long, thin fibrils that cross-link to one another in the spaces around cells. The cross-links result in the formation of very strong, mature type V collagen fibers. Type V collagen can be detected in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen.
參考文獻(xiàn)
Greenspan DS. et al., 1992, Genomics. 12 (4): 836-7.
Mann K. 1992, Biol Chem Hoppe-Seyler. 373 (2): 69-75.
Greenspan DS. et al., 1992, Gene Expr. 1 (1): 29-39.
規(guī)格:20ug
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