STC2 / Stanniocalcin 2蛋白產(chǎn)品信息
別名: STC2
表達(dá)方式:
A DNA sequence encoding the human STC2 (O76061) (Met1-Arg302) was expressed with a C-terminal polyhistidine tag.
種屬: Human
表達(dá)宿主: Human Cells
STC2 / Stanniocalcin 2 Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Thr 25
分子量:
The recombinant human STC2 comprises 289 amino acids and has a predicted molecular mass of 32.1 kDa. The apparent molecular mass of the protein is approximately 35-42 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
STC2 / Stanniocalcin 2 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
STC2 / Stanniocalcin 2蛋白背景綜述
STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It is a secreted, homodimeric glycoprotein which expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. STC2 may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis.
參考文獻(xiàn)
Chang AC. et al., 1998, Mol Cell Endocrinol. 141 (1-2): 95-9.
Ishibashi K. et al., 1998, Biochem Biophys Res Commun. 250 (2): 252-8.
Uo CW. et al., 2005, Endocrinology. 146 (1): 469-76.
規(guī)格:50ug
關(guān) 鍵 詞:STC2 / Stanniocalcin 2 Protein,STC2 / Stanniocalcin 2蛋白質(zhì),廠家現(xiàn)貨,技術(shù)資料,實驗室耗材,生化試劑,上海創(chuàng)賽,博飛美科,實驗儀器,廠家
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