PROC1 / Protein C / PROC蛋白產(chǎn)品信息

別名: PROC
表達方式: 
A DNA sequence encoding the human PROC (P04070) (Met1-Pro461) was expressed with a C-terminal polyhistidine tag.
種屬: Human
表達宿主: Human Cells

PROC1 / Protein C / PROC Protein QC Testing

純度: (79+20.5) % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Thr 19
分子量: 
The recombinant human PROC comprises 454 amino acids and has a predicted molecular mass of 51.5 kDa. The apparent molecular mass of the protein is approximately 56-64 and 45 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

PROC1 / Protein C / PROC Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

PROC1 / Protein C / PROC蛋白背景綜述

PROC, also known as protein C and coagulation factor XIV, is a zymogenic (inactive) protein. Its activated form is a vitamin K-dependent serine protease which belongs the peptidase S1 family. PROC's activated form plays an important role in regulating blood clotting, inflammation, cell death, and maintaining the permeability of blood vessel walls in humans and other animals. PROC contains a two-chain polypeptide consisting of a light chain and a heavy chain connected by a disulfide bond. Defects in PROC cause thrombophilia which is a hemostatic disorder characterized by impaired regulation of blood coagulation and a tendency to recurrent venous thrombosis.

參考文獻

Foster DC. et al., 1985, Proc Natl Acad Sci. 82 (14): 4673-7.
Hosac AM. 2002, Proc. 15 (2): 224-7.
D'Ursi P. et al., 2007, BMC Bioinformatics. 8 (1): S11.

規(guī)格：10ug

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