ADAM8蛋白產(chǎn)品信息

別名: ADAM8
表達方式: 
A DNA sequence encoding the cynomolgus ADAM8 (XP_002805919.1) (Met1-Pro497) was expressed with a polyhistidine tag at the C-terminus.
種屬: Cynomolgus
表達宿主: Human Cells

ADAM8 Protein QC Testing

純度: (50.8+34.6) % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Arg 21
分子量: 
The recombinant cynomolgus ADAM8 comprises 488 amino acids and has a calculated molecular mass of 53.6 KDa. The apparent molecular mass of it is approximately 47 and 66 KDa  in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile 12.5mM Tris, 5mM CaCl2, 75mM NaCl, 50% glycerol.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

ADAM8 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

ADAM8蛋白背景綜述

ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.

參考文獻

Yoshiyama K. et al., 1997, Genomics. 41 (1): 56-62.
Schlomann U. et al., 2001, J Neurosci. 20 (21): 7964-71.
Amour A. et al., 2002, FEBS Lett. 524 (1-3): 154-8.

規(guī)格：10ug

關(guān) 鍵 詞：Cynomolgus ADAM8 Protein,技術(shù)資料,廠家現(xiàn)貨，實驗室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實驗儀器，廠家

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