DCBLD2 / ESDN / CLCP1蛋白產(chǎn)品信息
別名: DCBLD2, CLCP1, ESDN
表達(dá)方式:
A DNA sequence encoding the human DCBLD2 (NP_563615.3) (Met1-Ala482) was expressed with a polyhistidine tag at the C-terminus.
種屬: Human
表達(dá)宿主: Human Cells
DCBLD2 / ESDN / CLCP1 Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Gln 21
分子量:
The recombinant human DCBLD2 consists of 473 amino acids and predicts a molecular mass of 52.6 KDa. It migrates as an approximately 69-89 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
DCBLD2 / ESDN / CLCP1 Protein Usage Guide
儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
DCBLD2 / ESDN / CLCP1蛋白背景綜述
DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor mediated signaling pathway, negative regulation of cell growth and so on.
參考文獻(xiàn)
Kobuke K. et al., 2001, J Biol Chem. 276 (36): 34105-14.
Adeghi MM. et al., 2007, Am J Transplant. 7 (9): 2098-105.
Chen Y. et al., 2007, Proteomics. 7 (14): 2384-97.
Park TJ. et al., 2012, J Korean Med Sci. 27 (4): 343-9.
規(guī)格:50ug
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