PNLIPRP1 / PLRP1蛋白產(chǎn)品信息
別名: PNLIPRP1, PLRP1
表達(dá)方式:
A DNA sequence encoding the human PNLIPRP1 (AAH25784.1) (Met1-Cys467) was expressed with a C-terminal polyhistidine tag.
種屬: Human
表達(dá)宿主: Human Cells
PNLIPRP1 / PLRP1 Protein QC Testing
純度: > 90 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Lys 18
分子量:
The recombinant human PNLIPRP1 comprises 461 amino acids and has a predicted molecular mass of 51.4 kDa. The apparent molecular mass of the protein is approximately 44-48 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
PNLIPRP1 / PLRP1 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
PNLIPRP1 / PLRP1蛋白背景綜述
PNLIPRP1, also known as PLRP1, belongs to the AB hydrolase superfamily, Lipase family. PNLIPRP1 is structurally similar to PLRP2. However, these two proteins display different functional properties. PNLIPRP1 may function as inhibitor of dietary triglyceride digestion. It lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters. PLRP2 hydrolyses milk fat with a lower catalytic efficiency than that of PL. PLRP2 activity, higher on homogenized than on native milk fat, is differently influenced by fatty acids and colipase depending on a proteolytic cleavage in the lid domain.
參考文獻(xiàn)
Grupe A. et al., 2006, Am J Hum Genet. 78 (1): 78-88.
Strausberg RL. et al., 2002, Proc Natl Acad Sci. 99 (26): 16899-903.
Giller T. et al., 1992, J Biol Chem. 267 (23): 16509-16.
規(guī)格:20ug
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