H7N9 (A/Shanghai/1/2013) 血凝素(HA / Hemagglutinin) 蛋白 Product Information
別名: HA
表達(dá)方式:
A DNA sequence encoding the Influenza A virus (A/Shanghai/1/2013 (H7N9)) (Met1-Val524) was expressed with a C-terminal polyhistidine tag.
種屬: Influenza A virus
表達(dá)宿主: Human Cells
H7N9 (A/Shanghai/1/2013) 血凝素(HA / Hemagglutinin) 蛋白 QC Testing
純度: > 85 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Asp 19
分子量:
The recombinant Influenza A virus (A/Shanghai/1/2013(H7N9)) comprises 517 amino acids and has a predicted molecular mass of 57.7 kDa. The apparent molecular mass of the protein is approximately 37-42 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
H7N9 (A/Shanghai/1/2013) 血凝素(HA / Hemagglutinin) 蛋白 Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
H7N9 (A/Shanghai/1/2013) 血凝素(HA / Hemagglutinin) 蛋白描述
H7N9 is a subtype of Influenza virus A. On April 1, 2013, the World Health Organization (WHO) first reported 3 human infections with a new influenza A (H7N9) virus in China. Since then, additional cases have been reported. This new H7N9 virus is an avian (bird) influenza (flu) virus. Influenza (flu) is a respiratory infection in mammals and birds. The virus is divided into three main types (Influenza A, Influenza B, and Influenza C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA)). The influenza viral Hemagglutinin (HA) protein is a homo trimer with a receptor binding pocket on the globular head of each monomer.
參考文獻(xiàn)
Günther-Ausborn S. et al., 2000, J Virol. 74: 2714-20.
Hoffman LR. et al., 1997, J Virol. 71: 8808-20.
Marjuki H. et al., 2006, J Biol Chem. 281: 16707-15.
Gething M-J. et al., 1980, Nature. 287: 301-6.
Naeve CW. et al.,1990, EMBO J. 9: 3857-66.
規(guī)格:50ug
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