TSPAN8 / Tetraspanin 8 / TM4SF3蛋白產(chǎn)品信息

別名: TSPAN8, TM4SF3
表達方式: 
A DNA sequence encoding the human TSPAN8 (P19075) (Lys110-Asn205) was expressed with the Fc region of mouse IgG1 at the N-terminus.
種屬: Human
表達宿主: Human Cells

TSPAN8 / Tetraspanin 8 / TM4SF3 Protein QC Testing

純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Asp
分子量: 
The recombinant human TSPAN8/mFc  comprises 332 amino acids and has a predicted molecular mass of 37.6 kDa. The apparent molecular mass of the monomer is approximately 46 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

TSPAN8 / Tetraspanin 8 / TM4SF3 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

TSPAN8 / Tetraspanin 8 / TM4SF3蛋白背景綜述

TSPAN8, also known as tetraspanin 8 and TM4SF3, is a member of the transmembrane 4 superfamily. Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. They mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN8 gene is expressed in different?carcinomas. TSPAN8 is a cell surface glycoprotein that is known to complex with?integrins. TSPAN8 is also known to efficiently induce angiogenesis in tumors and tumor-free tissues. However, little information exists on exosome-endothelial cell (EC) interactions or the proangiogenic role of tetraspanins. TSPAN8 contributed to a selective recruitment of proteins and mRNA into exosomes, including CD106 and CD49d.

參考文獻

Szala S. et al., 1990, Proc Natl Acad Sci. 87 (17): 6833-7.
Berditchevski F. et al., 2002, J Cell Sci. 114 (23): 4143-51.
Maruyama K. et al., 1994, Gene. 138 (1-2): 171-4.
Nazarenko I. et al., 2010, Cancer Res. 70 (4): 1668-78.

規(guī)格：50ug

關 鍵 詞：TSPAN8 / Tetraspanin 8 / TM4SF3 Protein，報價，廠家現(xiàn)貨，實驗室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實驗儀器，廠家

CANSPEC品質(zhì)提供的TSPAN8 / Tetraspanin 8 / TM4SF3 Protein|報價|廠家現(xiàn)貨性能**，其優(yōu)良的品質(zhì)滿足您不同實驗的多種需求。

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