RPRD1B蛋白產(chǎn)品信息

別名: RPRD1B, C20orf77, CREPT
表達(dá)方式: 
A DNA sequence encoding the human RPRD1B (AAH33629.1) (Met1-Asp326) was expressed with an N-terminal polyhistidine tag.
種屬: Human
表達(dá)宿主: Human Cells

RPRD1B Protein QC Testing

純度: > 85 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: His
分子量: 
The recombinant human RPRD1B comprises 346 amino acids and has a predicted molecular mass of 39.3 kDa. The apparent molecular mass of the protein is approximately 39 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

RPRD1B Protein Usage Guide

儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

RPRD1B蛋白背景綜述

RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phosphorylated RNAP II at target gene promoters. RNA polymerase II C-terminal domain (CTD) phosphorylation is important for various transcription-related processes. RPRD1B is a transcriptional regulator which enhances expression of CCND1. It also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A.

參考文獻(xiàn)

Ni Z. et al., 2011, Transcription. 2 (5): 237-42.
Kristensen AR. et al., 2012, Nat Methods. 9 (9): 907-9.
Woods NT. et al., 2012, Sci Signal.5 (242): rs6.

規(guī)格：20ug

關(guān) 鍵 詞：RPRD1B Protein,RPRD1B蛋白質(zhì),技術(shù)資料,現(xiàn)貨，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家

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