ART4蛋白產(chǎn)品信息

別名: ART4
表達(dá)方式: 
A DNA sequence encoding the cynomolgus ART4 (G7PJY0) (Thr31-Lys300) was expressed with the Fc region of human IgG1 at the C-terminus.
種屬: Cynomolgus
表達(dá)宿主: Human Cells

ART4 Protein QC Testing

純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Thr 31
分子量: 
The recombinant cynomolgus ART4 is a disulfide-linked homodimer. The reduced monomer comprises 480 amino acids and has a calculated molecular mass of 54.7 KDa.The apparent molecular mass of the protein is approximately 66 KDa respectively in SDS-PAGE.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

ART4 Protein Usage Guide

儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

ART4蛋白背景綜述

ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier molecule and CD297, belongs to a family of ectoenzymes named toxin-related ADP-ribosyltransferases (ARTs) that catalyze the transfer of ADP-ribose from NAD+ to a target protein. ART4 contains a mono-ADP-ribosylation motif. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. ART4 could be detected on HEL cells and erythrocytes by FACS analysis while it was absent from activated monocytes, despite the presence of ART4 mRNA in these cells. ART is also known as the carrier of the Dombrock blood group alloantigens (Do) which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane.

參考文獻(xiàn)

Parusel I. et al., 2005, Cell Immunol. 236 (1-2): 59-65.
Friedrich M. et al., 2005, DNA Seq. 16 (1): 53-7.
Okazaki IJ. et al., 1998, J Biol Chem. 273 (37): 23617-20.

規(guī)格：20ug

關(guān) 鍵 詞：Cynomolgus ART4 Protein,技術(shù)資料,廠家,參數(shù)，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家

CANSPEC品質(zhì)提供的Cynomolgus ART4 Protein|技術(shù)資料|廠家|參數(shù)性能**，其優(yōu)良的品質(zhì)滿足您不同實(shí)驗(yàn)的多種需求。

本產(chǎn)品由上海創(chuàng)賽品質(zhì)提供，歡迎咨詢國內(nèi)免費(fèi)服務(wù)專線：400-608-7598，更多產(chǎn)品信息請(qǐng)登錄www.ahbcpqn.cn 或 www.4006087598.com