LFA-3 / CD58蛋白產(chǎn)品信息
別名: CD58
表達方式:
A DNA sequence encoding the human CD58 (AAH05930.1) (Met1-Arg215) was expressed with a polyhistidine tag at the C-terminus.
種屬: Human
表達宿主: Human Cells
LFA-3 / CD58 Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Phe 29
分子量:
The recombinant human CD58 consists of 198 amino acids and predicts a molecular mass of 22.9 KDa. It migrates as an approximately 38-43 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
LFA-3 / CD58 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
LFA-3 / CD58蛋白背景綜述
CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.
參考文獻
Rochelle JM. et al., 1993, Int Immunol. 5 (2): 209-16.
Virtaneva KI. et al., 1993, Immunogenetics. 37 (6): 461-5.
Horejsí V. et al., 1991, FEBS Lett. 288 (1-2): 1-4.
規(guī)格:50ug
關(guān) 鍵 詞:LFA-3 / CD58 Protein,lfa 3 / CD58蛋白質(zhì),價格,現(xiàn)貨,實驗室耗材,生化試劑,上海創(chuàng)賽,博飛美科,實驗儀器,廠家
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