Serglycin / SRGN蛋白產(chǎn)品信息

別名: SRGN, PRG, PRG1
表達(dá)方式: 
A DNA sequence encoding the human SRGN (CAA34900.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus.
種屬: Human
表達(dá)宿主: Human Cells

Serglycin / SRGN Protein QC Testing

純度: > 95% as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Tyr 28
分子量: 
The recombinant human SRGN consists of  142 amino acids and predicts a molecular mass of 16.1 KDa. It migrates as an approximately 57 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

Serglycin / SRGN Protein Usage Guide

儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Serglycin / SRGN蛋白背景綜述

SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.

參考文獻(xiàn)

Hatton MN. et al., 1985, Biochem J. 230 (3): 817-20.
Schick BP. et al., 1995, J Cell Physiol. 165 (1): 96-106.
Kato S. et al., 1995, Gene. 150 (2): 243-50.

規(guī)格:50ug

關(guān) 鍵 詞：Serglycin / SRGN Protein，技術(shù)資料，價(jià)格，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家

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