ART3蛋白產(chǎn)品信息
別名: ART3, TMART
表達方式:
A DNA sequence encoding the human ART3(AAH08397.1) (Met1-Ser362) was expressed with a polyhistidine tag at the C-terminus.
種屬: Human
表達宿主: Human Cells
ART3 Protein QC Testing
純度: > 90% as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Glu 27
分子量:
The recombinant human ART3 consists of 347 amino acids and predicts a molecular mass of 39.6 KDa. It migrates as an approximately 49 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
ART3 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
ART3蛋白背景綜述
ADP-ribosyltransferase 3 / ART3 Protein Description ADP-ribosyltransferase 3, also known as ART3, is an arginine-specific ADP-ribosyltransferase. It is a member of the Arg-specific ADP-ribosyltransferase family. It is expressed specifically in testis. ADP-ribosyltransferase 3 catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. ADP-ribosyltransferase 3 pseudogene is located on chromosome 11. ART3 was identified as a susceptibility gene for non-obstructive azoospermia (NOA). It is a novel therapeutic target in the treatment of NOA.
參考文獻
Lévy I. et al., 1996, FEBS Lett. 382 (3): 276-80.
Suzuki Y. et al., 1997, Gene. 200 (1-2): 149-56.
Balducci E. et al., 1999, Am J Respir. 21 (3): 337-46.
規(guī)格:20ug
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