MBD2 / DPEP2蛋白產(chǎn)品信息
別名: DPEP2
表達(dá)方式:
A DNA sequence encoding the human DPEP2 (AAH24021.1) (Met1-Ser376) was expressed with a polyhistidine tag at the C-terminus.
種屬: Human
表達(dá)宿主: Human Cells
MBD2 / DPEP2 Protein QC Testing
純度: > 90% as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Ala 33
分子量:
The recombinant human DPEP2 consists of 355 amino acids and predicts a molecular mass of 39.4 KDa. It migrates as an approximately 47 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS , pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
MBD2 / DPEP2 Protein Usage Guide
儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
MBD2 / DPEP2蛋白背景綜述
MBD2, also known as DPEP2, is a nuclear protein. It belongs to a family related by the presence in each of a methyl-CpG-binding domain (MBD). Besides MBD2, the family members also include MECP2, MBD1, MBD3, and MBD4. Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1, and MBD2 can also repress transcription from methylated gene promoters. It is reported that MBD2 functions as a demethylase. MBD2 may function as a mediator of the biological consequences of the methylation signal.
參考文獻(xiàn)
Hendrich B. et al., 1999, Mamm Genome. 10 (9): 906-12.
Brackertz. et al., 2002, J Biol Chem. 277 (43): 40958-66.
Zhang Y. et al., 1999, Nat Genet. 23 (1): 58-61.
規(guī)格：20ug
關(guān) 鍵 詞：MBD2 / DPEP2 Protein,MBD2 / DPEP2蛋白質(zhì),技術(shù)資料,現(xiàn)貨，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家
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