IFNA13 / Interferon alpha-13蛋白產(chǎn)品信息

別名: IFNA13
表達方式: 
A DNA sequence encoding the cynomolgus IFNA13(G7NFW4) (Met1-Glu190) was expressed with the Fc region of human IgG1 at the C-terminus.
種屬: Cynomolgus
表達宿主: Human Cells

IFNA13 / Interferon alpha-13 Protein QC Testing

純度: > 85 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Cys 25
分子量: 
The recombinant cynomolgus IFNA13 is a disulfide-linked homodimer. The reduced monomer comprises 407 amino acids and has a calculated molecular mass of 46.4 KDa.The apparent molecular mass of the protein is approximately 47 KDa respectively in SDS-PAGE.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

IFNA13 / Interferon alpha-13 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IFNA13 / Interferon alpha-13蛋白背景綜述

Interferon alpha-13, also known as IFN-alpha-13, Interferon alpha-D, and IFNA13, is a secreted protein which belongs to the alpha / beta interferon family. Interferon alpha-13 / IFNA13 is produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, or parasites or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs belong to the large class of glycoproteins known as cytokines. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection.

參考文獻

Humphray SJ. et al., 2004, Nature. 429: 369-74.
Liu YJ. et al., 2005, Annu Rev Immunol. 23: 275-306.
Fensterl V. et al., 2009, Biofactors. 35 (1): 14-20.

規(guī)格：50ug

關(guān) 鍵 詞：Cynomolgus IFNA13 / Interferon alpha-13 Protein,價格,廠家現(xiàn)貨，實驗室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實驗儀器，廠家

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