NCR1蛋白產(chǎn)品信息

別名: NCR1, Ar1, Kilr1, Ly94
表達(dá)方式: 
A DNA sequence encoding the rat NCR1 (Q9Z0H5) (Met1-Asn255) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
種屬: Rat
表達(dá)宿主: Human Cells

NCR1 Protein QC Testing

純度: (73.6+23)%as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Gln 17
分子量: 
The recombinant rat NCR1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 480 amino acids and has a predicted molecular mass of 54.1 kDa. The apparent molecular mass of the protein is approximately 65 and 36 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

NCR1 Protein Usage Guide

儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

NCR1蛋白背景綜述

NCR1, also known as NK-p46 and CD335, is called natural cytotoxicity receptors (NCR) together with NCR3 and NCR2. NKp46 has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. It has been implicated in NK cell-mediated lysis of several autologous tumor cells, pathogen-infected cell lines and mononuclear phagocytes infected with an intracellular bacterium. NKp46 is a surface receptor involved in NK-cell cell death by apoptosis. NKp46 and its coreceptor CD59 together activate cytotoxicity of human NK-cells, their engagement results in tyrosine phosphorylation of CD3-zeta chains associated with NKp46.

參考文獻(xiàn)

Carbone E. et al., 2005, Blood. 105 (1): 251-8.
Sivori S. et al., 1997, J Exp Med. 186 (7): 1129-36.
Biassoni R. et al., 2004, J Cell Mol Med. 7 (4): 376-87.

規(guī)格：50ug

關(guān) 鍵 詞：Rat NCR1 Protein,技術(shù)資料,價(jià)格，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家

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