VEGF-D / VEGFD / FIGF蛋白產(chǎn)品信息

別名: 
FIGF, Vegfd
表達方式: 
A DNA sequence encoding the mouse FIGF (P97946) (Phe98-Ser206) was expressed with a C-terminal polyhistidine tag.
種屬: Mouse
表達宿主: Human Cells

VEGF-D / VEGFD / FIGF Protein QC Testing

純度: > 95% as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Phe 98
分子量: 
The recombinant mouse FIGF comprises 120 amino acids and has a predicted molecular mass of 14 kDa. The apparent molecular mass of the protein is approximately 22 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH7.4
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

VEGF-D / VEGFD / FIGF Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

VEGF-D / VEGFD / FIGF蛋白背景綜述

Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), is a vascular endothelial growth factor. This secreted protein is a member of the platelet derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and performs activities in angiogenesis, lymphangiogenesis, and endothelial cell growth. Human VEGF-D is expressed in ***** lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. It is structurally and functionally similar to VEGF-C, and is secreted as a non-covelent homodimer in a antiparallel fashion. VEGF-D undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. Like VEGFC, it may particularly be involed in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in *****s.

參考文獻

Achen MG. et al., 1998, Proc Natl Acad Sci. 95 (2): 548-53.
Stacker SA. et al., 1999, J Biol Chem. 274: 32127-36.
Baldwin ME. et al., 2001, J Biol Chem. 276: 19166-71.
McColl BK. et al., 2003, J Exp Med. 198: 863-8.
Roy H. et al., 2006, FEBS Lett. 580: 2879-87.
Otrock ZH. et al., 2007, Blood Cells Mol Dis. 38: 258-68.

規(guī)格：20ug

關(guān) 鍵 詞：Mouse VEGF-D / VEGFD / FIGF Protein,產(chǎn)品詳情,價格，實驗室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實驗儀器，廠家

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