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Rat CD79B / B29 Protein|廠家現(xiàn)貨|產(chǎn)品詳情

產(chǎn)品名稱: Rat CD79B / B29 Protein|廠家現(xiàn)貨|產(chǎn)品詳情
產(chǎn)品型號(hào): C86-803-26
產(chǎn)品展商: 博飛美科
產(chǎn)品文檔: 無相關(guān)文檔

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Rat CD79B / B29 Protein|廠家現(xiàn)貨|產(chǎn)品詳情由上海創(chuàng)賽科學(xué)儀器有限公司品質(zhì)提供,可查詢Rat CD79B / B29 Protein價(jià)格。上海創(chuàng)賽科學(xué)儀器有限公司是專業(yè)**試劑生產(chǎn)及供應(yīng)商,其優(yōu)良的品質(zhì)滿足您不同實(shí)驗(yàn)的多種需求,更多產(chǎn)品詳情請(qǐng)登www.ahbcpqn.cn


Rat CD79B / B29 Protein|廠家現(xiàn)貨|產(chǎn)品詳情  的詳細(xì)介紹

CD79B / B29蛋白產(chǎn)品信息

別名: CD79B, B29/Ig-beta, Igb
表達(dá)方式: 
A DNA sequence encoding the rat CD79B(O70153)(Met1-Asp158) was expressed, fused with a polyhistidine tag at the C-terminus.
種屬: Rat
表達(dá)宿主: Human Cells

CD79B / B29 Protein QC Testing

純度: > 90 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Val 26
分子量: 
The recombinant rat CD79B comprises 144 amino acids and predicts a molecular mass of 16.8 kDa. The apparent molecular mass of  the recombinant protein is approximately 28 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CD79B / B29 Protein Usage Guide

儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CD79B / B29蛋白背景綜述

B-cell antigen receptor complex-associated protein beta chain, also known as B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b and B29, is a single-pass type I membrane protein which contains one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain. CD79b / B29 is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79b / B29 enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b / B29 are the cause of agammaglobulinemia type 6 (AGM6) which is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.

參考文獻(xiàn)

Mueller BS. et al., 1992, Eur J Immunol. 22: 1621-5.
Wood WJ. et al., 1993, Genomics. 16: 187-92.
Hashimoto S. et al., 1994, Immunogenetics. 40: 145-9.
Radaev S. et al., 2010, Structure. 18: 934-43.
Burkard TR. et al., 2011, BMC Syst Biol. 5: 17-17.

規(guī)格:20ug

關(guān) 鍵 詞:Rat CD79B / B29 Protein,廠家現(xiàn)貨,產(chǎn)品詳情,實(shí)驗(yàn)室耗材,生化試劑,上海創(chuàng)賽,博飛美科,實(shí)驗(yàn)儀器,廠家

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