TNFSF13蛋白產(chǎn)品信息
別名: TNFSF13, April
表達(dá)方式:
A DNA sequence encoding the mouse TNFSF13(Q9D777)(Ala96-Leu240) was expressed with the fused Fc region of human IgG1 at the N-terminus.
種屬: Mouse
表達(dá)宿主: Human Cells
TNFSF13 Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Glu
分子量:
The recombinant mouse TNFSF13/Fc comprises 405 amino acids and has a predicted molecular mass of 44.8 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
TNFSF13 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
TNFSF13蛋白背景綜述
TNFSF13 belongs to the tumor necrosis factor (TNF) ligand family. It exists as a functional homotrimer. It can bind to two cell surface receptors, BCMA and TACI, which it shares with BAFF to exert downstream T- and B-cell regulatory effects. It also possesses a heparin binding domain and has been demonstrated to bind to proteoglycans on the cell surface. TNFSF13 is a potential biomarker, with serum levels elevated for certain cancers and expression levels elevated in cancer tissues. It is also a potential biomarker for certain autoimmune diseases.
參考文獻(xiàn)
Bossen C. et al., 2007, Immunol. 18 (5): 263-75.
Tangye SG. et al., 2007, Immunol. 18 (5): 305-17.
Osman W. et al., 2012, PLoS One. 7 (4): e32683.
規(guī)格:20ug
關(guān) 鍵 詞:Mouse TNFSF13 Protein ,技術(shù)資料,廠家現(xiàn)貨,實驗室耗材,生化試劑,上海創(chuàng)賽,博飛美科,實驗儀器,廠家
CANSPEC品質(zhì)提供的Mouse TNFSF13 Protein |技術(shù)資料|廠家現(xiàn)貨性能**,其優(yōu)良的品質(zhì)滿足您不同實驗的多種需求。
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