TNFRSF17蛋白產(chǎn)品信息

別名: TNFRSF17
表達(dá)方式: 
A DNA sequence encoding the rat TNFRSF17 (D3ZKQ8) (Met1-Thr49) was expressed, fused  with the Fc region of human IgG1 at the N-terminus.
種屬: Rat
表達(dá)宿主: Human Cells

TNFRSF17 Protein QC Testing

純度: >99 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Glu
分子量: 
The recombinant Rat TNFRSF17/Fc is a disulfide-linked homodimer. The reduced monomer comprises 309 amino acids and has a predicted molecular mass of 34 kDa. The apparent molecular mass of the protein is approximately 40 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

TNFRSF17 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

TNFRSF17蛋白背景綜述

The tumor necrosis factor (TNF) receptor superfamily are a group of cell surface receptors critically involved in the maintenance of homeostasis of the immune system. By interacting with their corresponding ligands, these receptors either induce cell death or promote cell survival of immune cells. Human tumor necrosis factor receptor superfamily member 17, also known as B-cell maturation protein, TNFRSF17, BCMA, and CD269, is a single-pass type I II membrane protein which contains one TNFR-Cys repeat. TNFRSF17 is a member of the TNF receptor superfamily, and is preferentially expressed in mature B lymphocytes. It binds specifically to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), as well as various TNFR-associated factor (TRAF) family members including TRAF1, TRAF2 and TRAF3 adaptor proteins, and thus transduces signals for cell survival and proliferation. Lacking a "death domain", overexpression of TNFRSF17 activates NF-kappa B and c-Jun N-terminal kinase. TNFRSF17 is also found in a perinulear Golgi-like structure.

參考文獻(xiàn)

Hatzoglou A. et al., 2000, J Immunol. 165 (3): 1322-1330.
Zhou T. et al., 2002, Immunol Res. 26 (1-3): 323-336.
Liu Y. et al., 2003, Nature. 423: 49-56.
Hymowitz SG. et al., 2005, J Biol Chem. 280: 7218-7227.

規(guī)格：50ug

關(guān) 鍵 詞：Rat TNFRSF17 Protein,鼠TNFRSF17蛋白質(zhì),生產(chǎn)廠家,價格，實(shí)驗(yàn)室耗材，生化試劑，上海創(chuàng)賽，博飛美科，實(shí)驗(yàn)儀器，廠家

CANSPEC品質(zhì)提供的Rat TNFRSF17 Protein|鼠TNFRSF17蛋白質(zhì)|生產(chǎn)廠家|價格性能**，其優(yōu)良的品質(zhì)滿足您不同實(shí)驗(yàn)的多種需求。

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