CTSS / Cathepsin-S蛋白產(chǎn)品信息
產(chǎn)品名稱：重組小鼠 CTSS / Cathepsin-S 蛋白|Cathepsin S Protein|產(chǎn)品詳情|價格
別名: Cat S
表達(dá)方式: A DNA sequence encoding the full length of mouse CTSS (AAB94925.1) (Met 1-Ile 340) was expressed, with a C-terminal polyhistidine tag.
種屬: Mouse
表達(dá)宿主: Human Cells

CTSS / Cathepsin-S蛋白質(zhì)控指標(biāo)
純度: > 90 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Val 18
分子量: The recombinant mouse CTSS consists of 334 amino acids and predicts a molecular mass of 37.6 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCTSS is approximately 33-38 KDa.
緩沖液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CTSS / Cathepsin-S蛋白使用指南
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CTSS / Cathepsin-S蛋白背景綜述
Cathepsin S (CTSS) is a lysosomal cysteine protease of the papain family and may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. CTSS is synthesized as inactive precursor of 331 amino acids consisting of a 15-aa signal peptide, a propeptide of 99 aa, and a mature polypeptide of 217 aa. It is activated in the lysosomes by a proteolytic cleavage of the propeptide. The deduced amino acid sequence contains only one potential N-glycosylation site located in the propeptide. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS).
參考文獻(xiàn)
Wiederanders B. 1992, J Biol Chem. 267: 13708-13.
Shi GP. et al., 1994, J Biol Chem. 269: 11530-6.
Lemere CA. 1995, Am J Pathol. 146: 848-60.

包裝：10ug

1、產(chǎn)品質(zhì)量問題，在產(chǎn)品售出7日內(nèi)提出異議并且產(chǎn)品未有損壞，試劑類產(chǎn)品，需要提供詳細(xì)的檢測數(shù)據(jù)，創(chuàng)賽負(fù)責(zé)免費退換貨服務(wù)；
2、本產(chǎn)品屬于消耗品，不提供質(zhì)保服務(wù)；
3、所有產(chǎn)品售后問題，請直接聯(lián)系我司，我們將會盡快為您響應(yīng)處理
查詢關(guān)鍵詞：重組小鼠 CTSS / Cathepsin-S 蛋白,Cathepsin S Protein,產(chǎn)品詳情,價格，原料藥，大包裝定制，現(xiàn)貨促銷，醫(yī)藥中間體，科學(xué)儀器，實驗室耗材，生化試劑，創(chuàng)賽中國,細(xì)胞因子
CANSPEC品質(zhì)提供的重組小鼠 CTSS / Cathepsin-S 蛋白|Cathepsin S Protein|產(chǎn)品詳情|價格性能**，其優(yōu)良的品質(zhì)滿足您不同實驗的多種需求。
本產(chǎn)品由上海創(chuàng)賽品質(zhì)提供，歡迎咨詢國內(nèi)免費服務(wù)專線：400-608-7598，更多產(chǎn)品信息請登錄www.ahbcpqn.cn或www.4006087598.com