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重組人 CXCL10 / Crg-2 蛋白|Chemokine (C-X-C motif) ligand 10 Protein|產(chǎn)品詳情|價(jià)格

產(chǎn)品名稱(chēng): 重組人 CXCL10 / Crg-2 蛋白|Chemokine (C-X-C motif) ligand 10 Protein|產(chǎn)品詳情|價(jià)格
產(chǎn)品型號(hào): C86-107-68
產(chǎn)品展商: 博飛美科
產(chǎn)品文檔: 無(wú)相關(guān)文檔

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重組人 CXCL10 / Crg-2 蛋白|Chemokine (C-X-C motif) ligand 10 Protein|產(chǎn)品詳情|價(jià)格由上海創(chuàng)賽科學(xué)儀器有限公司品質(zhì)提供。上海創(chuàng)賽科學(xué)儀器有限公司是專(zhuān)業(yè)**試劑生產(chǎn)及供應(yīng)商,其優(yōu)良的品質(zhì)滿足您不同實(shí)驗(yàn)的多種需求,歡迎撥打4006087598洽談選購(gòu),更多產(chǎn)品詳情請(qǐng)登錄www.ahbcpqn.cn


重組人 CXCL10 / Crg-2 蛋白|Chemokine (C-X-C motif) ligand 10 Protein|產(chǎn)品詳情|價(jià)格  的詳細(xì)介紹

CXCL10 / Crg-2蛋白產(chǎn)品信息
產(chǎn)品名稱(chēng):重組人 CXCL10 / Crg-2 蛋白|Chemokine (C-X-C motif) ligand 10 Protein|產(chǎn)品詳情|價(jià)格
別名: CXCL10, INP10, SCYB10
表達(dá)方式: A DNA sequence encoding the mature form of human CXCL10  (Q9UBH0) (Val22-Pro98) was expressed, with a N-terminal Met.
種屬: Human
表達(dá)宿主: E.coli

CXCL10 / Crg-2 Protein QC Testing
純度: > 90 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: Please contact us for more information.
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Met
分子量: The recombinant human CXCL10  consists of  78 amino acids and predicts a molecular mass of 8.8 KDa. It migrates as an approximately 9 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CXCL10 / Crg-2 Protein Usage Guide
儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CXCL10 / Crg-2蛋白背景綜述
CXCL10, also known as crg-2, belongs to the intercrine alpha (chemokine CxC) family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. With a three-dimensional crystal structure, CXCL10’s signaling is mediated by the g protein-coupled receptor CXCR3, which is expressed on activated T cells and plays an important role in directing the migration of T cells, especially during Th1 responses. It is secreted by monocytes, epithelial cells, and endothelial cells in response to IFN gamma or other pro-inflammatory cytokines and stimuli. Binding of CXCL10 to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. It is chemotactic for monocytes and T-lymphocytes. Baseline pre-treatment plasma levels of CXCL10 are elevated in patients chronically infected with hepatitis C virus (HCV) of genotypes 1 or 4.
參考文獻(xiàn)
O'Donovan N. et al., 1999, Cell Genet. 84 (1-2): 39-42.
Swaminathan GJ. et al., 2003, Structure. 11 (5): 521-32.
Booth V. et al., 2002, Biochemistry. 41 (33): 10418-25.

包裝:50ug

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