CCL17 / SCYA17蛋白產(chǎn)品信息
產(chǎn)品名稱：重組人 CCL17 / TARC / SCYA17 蛋白|CCL17 / SCYA17 Protein|技術(shù)資料|生產(chǎn)廠家
別名: A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17,  TARC
表達(dá)方式: A DNA sequence encoding the human CCL17 ( Q92583-1 ) ( Met 1 - Ser 94 ) was expressed and purified
種屬: Human
表達(dá)宿主: Baculovirus

CCL17 / SCYA17蛋白質(zhì)控指標(biāo)
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Ala 24
分子量: The secreted recombinant human CCL17 consists of 71 amino acids and predicts a molecular mass of 8 kDa. It migrates as an approximately 10 kDa band in SDS-PAGE under reducing conditions
緩沖液: Lyophilized from sterile PBS , pH 7.5
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CCL17 / SCYA17蛋白使用指南
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CCL17 / SCYA17蛋白背景綜述
C-C motif chemokine 17, also known as CC chemokine TARC, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CCL17 and SCYA17, is a secreted protein which belongs to the intercrine beta (chemokine CC) family. Chemokines are known to regulate the steady-state and inflammatory migration of cutaneous dendritic cells (DCs). The beta-chemokine CCL17, a ligand of CCR4, is inducibly expressed in a subset of DCs and is strongly up-regulated in atopic diseases. CCL17 / SCYA17 is constitutively expressed in the thymus and is produced by dendritic cells (DC), endothelial cells, keratinocytes (KC) and fibroblasts. CCL17 / SCYA17 is expressed at high levels in thymus and at low levels in the lung, colon and small intestine. CCL17 / SCYA17 is a chemotactic factor for T-lymphocytes but not monocytes or granulocytes. It may play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. CCL17 / SCYA17 binds to CCR4.Chemokine receptor CCR4 and its ligands (CCL17 and CCL22) are important for the recruitment of memory T cells into the skin in various cutaneous immune diseases.
參考文獻(xiàn)
Belperio,J.A. et al., 2004, J Immunol. 173 (7):4692-8.
Carpenter,K.J. et al., 2005, Infect Immun. 73 (11):7198-207.
Saeki,H. et al., 2006, J Dermatol Sci. 43 (2):75-84.
Niens,M. et al., 2008, Br J Haematol. 140 (5):527-36.
Stutte,S. et al., 2010, Proc Natl Acad Sci. USA 107 (19):8736-41.

包裝：20ug

1、產(chǎn)品質(zhì)量問題，在產(chǎn)品售出7日內(nèi)提出異議并且產(chǎn)品未有損壞，試劑類產(chǎn)品，需要提供詳細(xì)的檢測數(shù)據(jù)，創(chuàng)賽負(fù)責(zé)免費(fèi)退換貨服務(wù)；
2、本產(chǎn)品屬于消耗品，不提供質(zhì)保服務(wù)；
3、所有產(chǎn)品售后問題，請直接聯(lián)系我司，我們將會盡快為您響應(yīng)處理
查詢關(guān)鍵詞：重組人 CCL17 / TARC / SCYA17 蛋白,CCL17 / SCYA17 Protein,技術(shù)資料,生產(chǎn)廠家，原料藥，大包裝定制，現(xiàn)貨促銷，醫(yī)藥中間體，科學(xué)儀器，實(shí)驗(yàn)室耗材，生化試劑，創(chuàng)賽中國,細(xì)胞因子
CANSPEC品質(zhì)提供的重組人 CCL17 / TARC / SCYA17 蛋白|CCL17 / SCYA17 Protein|技術(shù)資料|生產(chǎn)廠家性能**，其優(yōu)良的品質(zhì)滿足您不同實(shí)驗(yàn)的多種需求。
本產(chǎn)品由上海創(chuàng)賽品質(zhì)提供，歡迎咨詢國內(nèi)免費(fèi)服務(wù)專線：400-608-7598，更多產(chǎn)品信息請登錄www.ahbcpqn.cn或www.4006087598.com