EFNB2 / EphrinB2蛋白產(chǎn)品信息
產(chǎn)品名稱：重組大鼠 EFNB2 / EphrinB2 蛋白|Ephrin B2 Protein|生產(chǎn)廠家|現(xiàn)貨
別名: Efnb2 Efnb2_predicted
表達(dá)方式: A DNA sequence encoding the rat EFNB2(NP_001100798.1) (Met1-Ala229) was expressed, fused with a polyhistidine tag at the C-terminus.
種屬: Rat
表達(dá)宿主: Human Cells

EFNB2 / EphrinB2 Protein QC Testing
純度: > 99 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測(cè)N端: Arg 29
分子量: The recombinant rat EFNB2 comprises 212 amino acids and has a predicted molecular mass of 23.5 kDa. The apparent molecular mass of the protein is approximately 33-39 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

EFNB2 / EphrinB2 Protein Usage Guide
儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

EFNB2 / EphrinB2蛋白背景綜述
The ephrins (Eph) and Eph receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosyl- phosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. All ephrins share a conserved extracellular sequence, which most likely corresponds to the receptor-binding domain. This conserved sequence consists of approximately 125 amino acids and includes four invariant cysteines. The cytoplasmic domains are approximately 80 amino acids long and are highly conserved, especially the last 33 amino acids. In molecular biology, ephrins and Eph receptors are components of cell signaling pathways involved in animal development, and implicated in some cancers. Eph receptors are classified as receptor tyrosine kinases (RTKs), and form the largest sub-family of RTKs. Almost all Eph receptors are expressed during various well defined stages of development in assorted locations and concentrations. Ephrin-B2 is a member of the ephrin ligand family, which binds members of the Eph receptor family. It has been shown to bind EphA4, EphB1, EphB2, EphB3, and EphB4. Ephrin-B2 plays a role in a variety of developmental processes, including arterial-venous differentiation, neural crest cell migration, and axon guidance.
參考文獻(xiàn)
Cerretti DP. et al., 1995, Mol Immunol. 32 (16): 1197-205.
Gale NW. et al.,1996, Neuron.17 (1): 9-19.
Flanagan J. et al., 1998, Annual Review of Neuroscience. 21: 309-45.
Holder N. et al., 1999, Development. 126 (10): 2033-44.
Wilkinson DG. et al., 2001, Nat. Rev. Neurosci. 2 (3): 155-64.
Murai KK. et al., 2003, Journal of Cell Science. 116: 2823-32.

包裝：200ug

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查詢關(guān)鍵詞：重組大鼠 EFNB2 / EphrinB2 蛋白，Ephrin B2 Protein，生產(chǎn)廠家，現(xiàn)貨，原料藥，大包裝定制，現(xiàn)貨促銷，醫(yī)藥中間體，科學(xué)儀器，實(shí)驗(yàn)室耗材，生化試劑，創(chuàng)賽中國(guó),細(xì)胞因子
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