EFNB2 / EphrinB2蛋白產(chǎn)品信息
產(chǎn)品名稱：重組小鼠 EFNB2 / EphrinB2 蛋白|Mouse EFNB2 / Ephrin-B2 Protein|參數(shù)|價(jià)格
別名: Efnb2， ELF-2,  Epl5,  Eplg5,  Htk-L,  LERK-5,  Lerk5,  NLERK-1
表達(dá)方式: A DNA sequence encoding the mouse EFNB2 (NP_034241.2) extracellular domain (Met 1-Ala 232) was fused with a polyhistidine tag at the C-terminus
種屬: Mouse   
表達(dá)宿主: Human Cells

EFNB2 / EphrinB2蛋白質(zhì)控指標(biāo)
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內(nèi)**: < 1.0 EU per μg of the protein as determined by the LAL method
穩(wěn)定性: Samples are stable for up to twelve months from date of receipt at -70℃
預(yù)測N端: Arg 29
分子量: The secreted recombinant mouse EFNB2 comprises 215 amino acids and has a predicted molecular mass of 23.5 kDa. As a result of glycosylation, the apparent molecular mass of rmEFNB2 is approximately 30-40 kDa in SDS-PAGE under reducing conditions
緩沖液: Lyophilized from sterile PBS , pH 7.4
EFNB2 / EphrinB2蛋白使用指南
儲(chǔ)存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
EFNB2 / EphrinB2蛋白背景綜述
The ephrins (Eph) and Eph receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosyl- phosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. All ephrins share a conserved extracellular sequence, which most likely corresponds to the receptor-binding domain. This conserved sequence consists of approximately 125 amino acids and includes four invariant cysteines. The cytoplasmic domains are approximately 80 amino acids long and are highly conserved, especially the last 33 amino acids. In molecular biology, ephrins and Eph receptors are components of cell signaling pathways involved in animal development, and implicated in some cancers. Eph receptors are classified as receptor tyrosine kinases (RTKs), and form the largest sub-family of RTKs. Almost all Eph receptors are expressed during various well defined stages of development in assorted locations and concentrations. Mouse Ephrin-B2 is a member of the ephrin ligand family, which binds members of the Eph receptor family. It has been shown to bind EphA4, EphB1, EphB2, EphB3, and EphB4. Ephrin-B2 plays a role in a variety of developmental processes, including arterial-venous differentiation, neural crest cell migration, and axon guidance.
參考文獻(xiàn)
Cerretti, DP. et al., 1995, Mol. Immunol. 32 (16): 1197-205.
Gale, NW. et al.,1996, Neuron.17 (1): 9-19.
Flanagan, J. et al., 1998, Annual Review of Neuroscience. 21: 309-45.
Holder, N. et al., 1999,  Development. 126 (10): 2033-44.
Wilkinson, DG. et al., 2001, Nat. Rev. Neurosci. 2 (3): 155-64.
Murai, KK. et al., 2003, Journal of Cell Science. 116 (Pt 14): 2823-32.

包裝：100ug

1、產(chǎn)品質(zhì)量問題，在產(chǎn)品售出7日內(nèi)提出異議并且產(chǎn)品未有損壞，試劑類產(chǎn)品，需要提供詳細(xì)的檢測數(shù)據(jù)，創(chuàng)賽負(fù)責(zé)免費(fèi)退換貨服務(wù)；
2、本產(chǎn)品屬于消耗品，不提供質(zhì)保服務(wù)；
3、所有產(chǎn)品售后問題，請(qǐng)直接聯(lián)系我司，我們將會(huì)盡快為您響應(yīng)處理
查詢關(guān)鍵詞：重組小鼠 EFNB2 / EphrinB2 蛋白，Mouse EFNB2 / Ephrin-B2 Protein，參數(shù)，價(jià)格，原料藥，大包裝定制，現(xiàn)貨促銷，醫(yī)藥中間體，科學(xué)儀器，實(shí)驗(yàn)室耗材，生化試劑，創(chuàng)賽中國,細(xì)胞因子
CANSPEC品質(zhì)提供的重組小鼠 EFNB2 / EphrinB2 蛋白|Mouse EFNB2 / Ephrin-B2 Protein|參數(shù)|價(jià)格性能**，其優(yōu)良的品質(zhì)滿足您不同實(shí)驗(yàn)的多種需求。
本產(chǎn)品由上海創(chuàng)賽品質(zhì)提供，歡迎咨詢國內(nèi)免費(fèi)服務(wù)專線：400-608-7598，更多產(chǎn)品信息請(qǐng)登錄www.ahbcpqn.cn或www.4006087598.com