產(chǎn)品名稱:PE 小鼠抗人 CD138 抗體;PE Mouse Anti-Human CD138
中文名稱:PE Mouse Anti-Human CD138
英文名稱:PE Mouse Anti-Human CD138
PE Mouse Anti-Human CD138 產(chǎn)品介紹:
Material Number: 550805
Alternate Name: Syndecan-1
Size: 100 tests
Vol. per Test: 20 μl
Clone: DL-101
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: NA
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
PE Mouse Anti-Human CD138 Description:
Reacts with CD138 (Syndecan-1), an 85-92 kDa single chain transmembrane protein, expressed on multiple myeloma-derived cell lines and
malignant plasma cell populations. It is also expressed on pre-B cells, immature B cells and plasma cells, but not on mature circulating
B-lymphocytes. Syndecan-1 is a member of the family of transmembrane heparan sulfate proteoglycans. It is also expressed on some
non-hematopoietic cells, including embryonic mesenchymal cells, vascular smooth muscle cells, endothelial and neural cells. CD138 binds to
many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III and V, tenascin, thrombospondin, and antithrombin III. It is considered an extracellular matrix receptor that may serve as a co-receptor for fibroblast growth factor and related molecules. Monoclonal antibody DL-101 does not block the binding of clone B-B4 (another anti-syndecan-1 antibody) or
Mi15 by flow cytometric analysis.
PE Mouse Anti-Human CD138 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.