PE Active Caspase-3 Apoptosis Kit
產(chǎn)品名稱: PE Active Caspase-3 Apoptosis Kit
產(chǎn)品型號: BD-550914
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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PE Active Caspase-3 Apoptosis Kit
的詳細(xì)介紹
產(chǎn)品名稱:PE Active Caspase-3 Apoptosis Kit
PE Active Caspase-3 Apoptosis Kit 產(chǎn)品介紹：
Material Number: 550914
Reactivity: QC Testing: Human
Tested in Development: Mouse
Component: 51-68655X
Description: PE Rabbit Anti- Active Caspase-3 (CPP32; Yama; Apopain)
Size: 100 Tests (1 ea)
Vol. per Test: 20 μl
Clone Name: C92-605
Immunogen: Human Active Caspase-3 Fragment
Isotype: Rabbit IgG
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Component: 51-6896KC
Description: Cytofix/Cytoperm? Fixation and Permeabilization Solution (1X)
Size: 65 ml (1 ea)
Storage Buffer: Aqueous buffered solution containing paraformaldehyde and saponin.
Component: 51-6897KC
Description: Perm/Wash? Buffer (10X Solution)
Size: 65 ml (1 ea)
Storage Buffer: Aqueous buffered solution containing saponin, fetal bovine serum and ≤ 0.09%
sodium azide.
PE Active Caspase-3 Apoptosis Kit Description：
The caspase family of cysteine proteases plays a key role in apoptosis and inflammation. Caspase-3 is a key protease that is activated during
the early stages of apoptosis and, like other members of the caspase family, is synthesized as an inactive pro-enzyme that is processed in cells
undergoing apoptosis by self-proteolysis and/or cleavage by another protease. The processed forms of caspases consist of large (17-22 kDa)
and small (10-12 kDa) subunits which associate to form an active enzyme. Active caspase-3, a marker for cells undergoing apoptosis, consists
of a heterodimer of 17 and 12 kDa subunits which is derived from the 32 kDa pro-enzyme. Active caspase-3 proteolytically cleaves and
activates other caspases, as well as relevant targets in the cytoplasm, e.g., D4-GDI and Bcl-2, and in the nucleus (e.g. PARP). This antibody
has been reported to specifically recognize the active form of caspase-3 in human and mouse cells. It has not been reported to recognize the
pro-enzyme form of caspase-3.
PE Active Caspase-3 Apoptosis Kit Preparation and Storage：
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
PE Active Caspase-3 Apoptosis Kit Product Notices：
1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
