產(chǎn)品名稱:Purified 小鼠抗大鼠 CD73 抗體；Purified Mouse Anti-Rat CD73

中文名稱:Purified 小鼠抗大鼠 CD73 抗體

英文名稱:Purified Mouse Anti-Rat CD73

Purified Mouse Anti-Rat CD73 產(chǎn)品介紹：

Material Number: 551123
Alternate Name: Ecto-5'-nucleotidase
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: 5F/B9
Immunogen: Ecto-5'-nucleotidase purified from rat renal membranes
Isotype: Mouse (BALB/c) IgG1, κ
Reactivity: QC Testing: Rat
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide

Purified Mouse Anti-Rat CD73 Description：

The 5F/B9 antibody reacts with CD73 or Ecto-5'-nucleotidase (5'-NT), a 68-kDa GPI-anchored cell-surface protein with enzymatic and signal 
transduction activities. 5'-NT catalyzes the dephosphorylation of extracellular nucleoside 5' monophosphates into a form which can enter cells 
to meet their metabolic needs. It also regulates the concentration of extracellular adenosine, which initiates a variety of physiological responses 
through the adenosine receptors in many tissues. Membrane-bound and/or intracytoplasmic CD73 is found in a variety of organs and tissues, 
including liver, kidney, adrenal cortex, spleen, muscle, nervous tissue, and heart. The expression of CD73 on mouse leukocytes has been well 
characterized. In the rat, CD73 has been detected on subsets of peripheral B and T lymphocytes, NK cells, and granulocytes, as well as bone 
marrow myeloid cells and some CD4+CD8- thymocytes. The 5F/B9 mAb does not inhibit the enzymatic activity of 5’-NT. Although soluble 
or plate-bound 5F/B9 mAb by itself does not affect T lymphocyte proliferation, it is an effective co-stimulator with plate-bound anti-rat CD3 
mAb G4.18 (Cat. no. 554829). 

Purified Mouse Anti-Rat CD73 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store undiluted at 4°C.