FITC Mouse Anti-Human HLA-A2
產(chǎn)品名稱: FITC Mouse Anti-Human HLA-A2
產(chǎn)品型號(hào): BD-551285
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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FITC Mouse Anti-Human HLA-A2
的詳細(xì)介紹
產(chǎn)品名稱:FITC 小鼠抗人 HLA-A2 抗體;FITC Mouse Anti-Human HLA-A2
中文名稱:FITC 小鼠抗人 HLA-A2 抗體
英文名稱:FITC Mouse Anti-Human HLA-A2
FITC Mouse Anti-Human HLA-A2 產(chǎn)品介紹:
Material Number: 551285
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: BB7.2
Isotype: Mouse IgG2b, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
FITC Mouse Anti-Human HLA-A2 Description:
The monoclonal antibody BB7.2 reacts with a subunit of the human leukocyte antigen-A2 (HLA-A2), a class I molecule of the major
histocompatibility complex (MHC). The MHC gene locus encodes a group of highly polymorphic, cell-surface proteins that play a broad role
in the immune response to protein antigens. MHC molecules function by binding and presenting small antigenic protein fragments to
antigen-specific receptors expressed by T cells (TCR). Human (human leukocyte antigen/HLA) MHC molecules comprise two major classes,
MHC class I and class II. Functionally, class I MHC molecules can bind peptides derived from intracellular antigens (eg, viral and some
bacterial antigens) that are specifically recognized by CD8+ T cells, and class II MHC molecules recognize antigens derived from pathogens
multiplying in intracellular vesicles, and those derived from ingested extracellular bacteria. When presented on the cell surface by the MHC
class II molecules, these antigens are recognized by CD4+ T cells. TCR recognize both processed peptides bound to MHC, as well as regions
of the MHC molecule itself. CD4 and CD8 accessory molecules strengthen formation of the TCR-MHC complex through their interaction
with non-polymorphic regions of the MHC molecule.
FITC Mouse Anti-Human HLA-A2 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.