FITC Rat Anti-Mouse CD25
產(chǎn)品名稱: FITC Rat Anti-Mouse CD25
產(chǎn)品型號(hào): BD-553071
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無(wú)相關(guān)文檔
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上海創(chuàng)賽優(yōu)勢(shì)提供FITC Rat Anti-Mouse CD25，BD抗體現(xiàn)貨促銷FITC Rat Anti-Mouse CD25，BD抗體優(yōu)惠促銷FITC Rat Anti-Mouse CD254，歡迎來(lái)電咨詢：400-608-7598.
FITC Rat Anti-Mouse CD25
的詳細(xì)介紹
產(chǎn)品名稱:FITC 大鼠抗小鼠 CD25 抗體；FITC Rat Anti-Mouse CD25
中文名稱:FITC 大鼠抗小鼠 CD25 抗體
英文名稱:FITC Rat Anti-Mouse CD25
FITC Rat Anti-Mouse CD25 產(chǎn)品介紹：
Material Number: 553071
Alternate Name: IL-2 Receptor α chain, p55
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: 7D4
Immunogen: IL-2-dependent BALB/c mouse helper T-cell clone HT-2
Isotype: Rat (LEW) IgM, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide
FITC Rat Anti-Mouse CD25 Description：
The 7D4 antibody reacts with CD25, the low affinity IL-2 Receptor (IL-2Rα, p55) expressed on activated T and B lymphocytes from all
mouse strains tested. IL-2Rα by itself is not a signaling receptor. However, it can combine with IL-2 Receptor β (CD122) and γ (CD132)
chains to form high-affinity, signaling receptor complexes for IL-2. Resting T and B lymphocytes and resting and activated NK cells do not
express IL-2Rα. CD25 is transiently expressed at a low level during normal B-cell development in the bone marrow on the CD45R/B220low
TdT- sIg- Pre-B/Pre-B-II and CD45R/B220low TdT- sIgM+ sIgD- immature B stages, but not on the CD45R/B220low TdT+ sIg-
Pro-B/Pre-B-I stage nor on CD45R/B220high TdTsIgM+ sIgD+ mature B cells. It is expressed at a higher level during a very early stage of
T-cell development in fetal and ***** thymus. Peripheral CD25+ CD4+ T lymphocytes called regulatory T (Treg) cells are involved in the
maintenance of self-tolerance. It has also been reported that dendritic cells express CD25, recognized by mAb 7D4 (Cat. no. 553068). The
3C7 antibody recognizes an epitope of CD25 which is distinct from those recognized by mAbs 7D4 and PC61 (Cat. no. 553866), and it blocks
binding of IL-2 to CD25.
FITC Rat Anti-Mouse CD25 Preparation and Storage：
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
