Purified Hamster Anti-Mouse CD28
產(chǎn)品名稱: Purified Hamster Anti-Mouse CD28
產(chǎn)品型號(hào): BD-553295
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無(wú)相關(guān)文檔
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Purified Hamster Anti-Mouse CD28
的詳細(xì)介紹
產(chǎn)品名稱:Purified 倉(cāng)鼠抗小鼠 CD28 抗體；Purified Hamster Anti-Mouse CD28
中文名稱:Purified 倉(cāng)鼠抗小鼠 CD28 抗體
英文名稱:Purified Hamster Anti-Mouse CD28
Purified Hamster Anti-Mouse CD28 產(chǎn)品介紹：
Material Number: 553295
Size: 0.5 mg
Concentration: 0.5 mg/ml
Clone: 37.51
Immunogen: Mouse EL-4 (T-cell lymphoma) Cells
Isotype: Syrian Hamster IgG2, λ1
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
Purified Hamster Anti-Mouse CD28 Description：
The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T
cells, and at even lower density on NK cells. The expression of CD28, in splenocytes and thymocytes, has been reported to increase after
activation. CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast
cells. It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes. CD28 is a costimulatory receptor;
its ligands include CD80 (B7-1) and CD86 (B7-2). The 37.51 mAb augments proliferation and cytokine production by activated T and NK
cells and can provide a costimulatory signal for CTL induction. There is considerable evidence that CD28 is a costimulatory receptor involved
in many, but not all, T cell-dependent immune responses
Purified Hamster Anti-Mouse CD28 Preparation and Storage：
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store undiluted at 4° C.
