Purified NA/LE Rat Anti-Mouse CD106
產(chǎn)品名稱: Purified NA/LE Rat Anti-Mouse CD106
產(chǎn)品型號: BD-553329
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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Purified NA/LE Rat Anti-Mouse CD106
的詳細介紹
產(chǎn)品名稱:Purified NA/LE 大鼠抗小鼠 CD106 抗體;Purified NA/LE Rat Anti-Mouse CD106
中文名稱:Purified NA/LE 大鼠抗小鼠 CD106 抗體
英文名稱:Purified NA/LE Rat Anti-Mouse CD106
Purified NA/LE Rat Anti-Mouse CD106 產(chǎn)品介紹:
Material Number: 553329
Alternate Name: Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: 429 (MVCAM.A)
Immunogen: Mouse preadipose cell line PA6
Isotype: Rat (LEW) IgG2a, κ
Reactivity: QC Testing: Mouse
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative,
0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of
protein as determined by the LAL assay.
Purified NA/LE Rat Anti-Mouse CD106 Description:
The 429 monoclonal antibody specifically binds to both the long (~110 kDa) transmembrane-spanning form and the truncated (~47 kDa)
GPI-linked form of vascular cell adhesion molecule-1 (VCAM-1, CD106). CD106 is constitutively expressed on bone marrow stromal cells,
myeloid cells, and splenic dendritic cells. Its expression on endothelial cells is upregulated by inflammatory cytokines and in certain
pathologic conditions. CD106 expression has also been detected on apoptotic thymocytes, splenocytes, and lymphoid cell lines. VCAM-1 is a
counter-receptor for VLA-4 (α4β1 integrin) and LPAM-1 (α4β7 integrin), and the 429 antibody partially blocks VCAM-1-mediated binding
functions. Source of the immunogen was the mouse preadipose cell line PA6.
Purified NA/LE Rat Anti-Mouse CD106 Preparation and Storage:
Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.