Purified Rat Anti-Mouse CD31
產(chǎn)品名稱(chēng): Purified Rat Anti-Mouse CD31
產(chǎn)品型號(hào): BD-553370
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無(wú)相關(guān)文檔
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上海創(chuàng)賽優(yōu)勢(shì)提供Purified Rat Anti-Mouse CD31，BD抗體現(xiàn)貨促銷(xiāo)Purified Rat Anti-Mouse CD31，BD抗體優(yōu)惠促銷(xiāo)Purified Rat Anti-Mouse CD31，歡迎來(lái)電咨詢(xún)：400-608-7598.
Purified Rat Anti-Mouse CD31
的詳細(xì)介紹
產(chǎn)品名稱(chēng):Purified 大鼠抗小鼠 CD31 抗體；Purified Rat Anti-Mouse CD31
中文名稱(chēng):Purified 大鼠抗小鼠 CD31 抗體
英文名稱(chēng):Purified Rat Anti-Mouse CD31
Purified Rat Anti-Mouse CD31 產(chǎn)品介紹：
Material Number: 553370
Alternate Name: PECAM-1
Size: 0.5 mg
Concentration: 0.5 mg/ml
Clone: MEC 13.3
Immunogen: 129/Sv mouse-derived endothelioma cell line tEnd.1
Isotype: Rat (LEW) IgG2a, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide
Purified Rat Anti-Mouse CD31 Description：
The MEC13.3 antibody reacts with CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1). CD31 is a 130 kDa
integral membrane protein, a member of the immunoglobulin superfamily, that mediates cell-to-cell adhesion. CD31 is expressed
constitutively on the surface of ***** and embryonic endothelial cells and is weakly expressed on many peripheral leukocytes and platelets. It
has also been detected on bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 is involved in the transendothelial
emigration of neutrophils, and neutrophil PECAM-1 appears to be down-regulated after extravasation into inflamed tissues. Multiple
alternatively spliced isoforms are detected during early post-implantation embryonic development; this alternative splicing is involved in the
regulation of ligand specificity. CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31.
CD31-mediated endothelial cell-cell interactions are involved in angiogenesis. The MEC13.3 mAb inhibits a variety of in vitro and in vivo
functions mediated by CD31.
Purified Rat Anti-Mouse CD31 Preparation and Storage：
Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography
