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產(chǎn)品資料

Biotin Mouse Anti-CD138

產(chǎn)品名稱: Biotin Mouse Anti-CD138
產(chǎn)品型號: BD-553713
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

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Biotin Mouse Anti-CD138  的詳細(xì)介紹

產(chǎn)品名稱:Biotin Mouse Anti-CD138

Biotin Mouse Anti-CD138 產(chǎn)品介紹:

Material Number: 553713
Alternate Name: Syndecan-1
Size: 0.5 mg
Concentration: 0.5 mg/ml
Clone: 281-2
Immunogen: NAMRU mouse mammary gland epithelial cell line NMuMG
Isotype: Rat (F344) IgG2a, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


Biotin Mouse Anti-CD138 Description:

The 281-2 antibody reacts with the core protein of CD138 (Syndecan-1), a cell-surface, integral membrane heparan sulfate- and chondroitin
sulfate-containing proteoglycan that binds to interstitial extracellular matrix molecules. Syndecan-1 is predominantly expressed on epithelial
cells, where its expression correlates with normal epithelial organization. It is also expressed on B lymphocytes at specific stages during their
differentiation: precursor B cells in the bone marrow and antibody-secreting cells, including plasma cells, but not mature peripheral B cells. It
is thus implicated in mediating B cell-matrix interactions. CD138 expression is also regulated during embryonic development, and the
molecule shows a tissue- specific structural polymorphism resulting from different post-translational modifications. The 281-2 antibody may
be used to detect the differently glycosylated forms, because it reacts with the core protein. Furthermore, the mAb detects the Syndecan-1
ectodomain which is cleaved from cell surfaces by a metalloproteinase


Biotin Mouse Anti-CD138 Preparation and Storage:

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.


Biotin Mouse Anti-CD138 Suggested Companion Products

Catalog Number Name Size Clone
554061 PE Streptavidin 0.5 mg (none)
553087 FITC Rat Anti-Mouse CD45R/B220 0.1 mg RA3-6B2
553928 Biotin Rat IgG2a κ Isotype Control 0.25 mg R35-95


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