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產(chǎn)品資料

PE Rat Anti-Mouse CD1d

產(chǎn)品名稱: PE Rat Anti-Mouse CD1d
產(chǎn)品型號: BD-553846
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

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PE Rat Anti-Mouse CD1d  的詳細介紹

產(chǎn)品名稱:PE 大鼠抗小鼠 CD1d 抗體;PE Rat Anti-Mouse CD1d

中文名稱:PE 大鼠抗小鼠 CD1d 抗體

英文名稱:PE Rat Anti-Mouse CD1d

PE Rat Anti-Mouse CD1d 產(chǎn)品介紹:

Material Number: 553846
Alternate Name: CD1.1, Ly-38
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: 1B1
Immunogen: Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma and mouse L929 
cells
Isotype: Rat (LEW) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.



PE Rat Anti-Mouse CD1d Description:

The 1B1 antibody reacts with CD1d, a 48-kDa glycoprotein with structural homology to the major histocompatibility complex (MHC) class I 
molecules. The structure, expression, and functions of CD1 antigens are complex and have been reviewed. mAb 1B1 detects CD1d at varying 
levels on most types of bone marrow and peripheral leukocytes and on epithelial, dendritic, and lymphoid cells in the thymus. It appears to 
recognize CD1d only in association with β2m. CD1d has been reported to be expressed by gastrointestinal tract epithelium and in the 
cytoplasm of hepatocytes as detected viaimmunohistochemical staining of frozen sections with mAb 3C11 (Cat. No. 559871, for the purified 
antibody), suggesting a possible role for CD1d in mucosal immunity. However, CD1d expression was not detectable, via flow cytometry, on 
intestinal epithelial cells in studies using the anti-CD1d mAbs 3C11, 1B1, and 9C7. The 1B1 antibody competes with mAb 3C11 in binding to 
mouse splenocytes. 



PE Rat Anti-Mouse CD1d Preparation and Storage:

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.




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