產(chǎn)品名稱:PE 大鼠抗小鼠 IL-10 抗體；PE Rat Anti-Mouse IL-10

中文名稱:PE 大鼠抗小鼠 IL-10 抗體

英文名稱:PE Rat Anti-Mouse IL-10

PE Rat Anti-Mouse IL-10 產(chǎn)品介紹：

Material Number: 554467
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: JES5-16E3
Immunogen: Recombinant mouse IL-10
Isotype: Rat IgG2b
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.



PE Rat Anti-Mouse IL-10 Description：

The JES5-16E3 monoclonal antibody specifically binds to the mouse cytokine, Interleukin-10 (IL-10). IL-10 is also known as Cytokine 
Synthesis Inhibitory Factor (CSIF). It is produced by various activated cell types including CD4+ T cells, CD8+ T cells, NK T cells, B1 B 
cells, NK cells, macrophages, dendritic cells, mast cells, granulocytes and keratinocytes. IL-10 plays a pivotal role in regulating immune 
responses and protecting the host from damage caused by inflammatory and autoimmune responses. IL-10 has numerous biological activities 
including the inhibition of cytokine synthesis by activated T cells, NK cells, monocytes, and macrophages. In the presence of accessory cells, 
IL-10 inhibits mitogen- or anti-CD3 induced proliferation of T lymphocytes. IL-10 has also been shown to costimulate the development of 
thymocytes, B cell differentiation and the generation of cytotoxic T cells. The immunogen used to generate the JES5-16E3 hybridoma was 
recombinant mouse IL-10. JES5-16E3 is a neutralizing antibody.

PE Rat Anti-Mouse IL-10 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.