產(chǎn)品名稱:Purified NA/LE 小鼠抗人 IFN-γ 抗體；Purified NA/LE Mouse Anti-Human IFN-γ
中文名稱:Purified NA/LE 小鼠抗人 IFN-γ 抗體
英文名稱:Purified NA/LE Mouse Anti-Human IFN-γ
Purified NA/LE Mouse Anti-Human IFN-γ 產(chǎn)品介紹：
Material Number: 554698
Alternate Name: IFNG; Interferon-gamma; Interferon-γ; Type II interferon; MAF
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: B27
Immunogen: Human IFN-γ Recombinant Protein
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative,
0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of
protein as determined by the LAL assay.
Purified NA/LE Mouse Anti-Human IFN-γ Description：
The B27 monoclonal antibody specifically binds to human interferon-γ (IFN-γ). IFN-γ is a potent multifunctional cytokine that is produced
by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ+ T cells. IFN-γ exerts its biological effects
through specific binding to the high-affinity IFN-γ Receptor Complex comprised of IFN-γRα (CD119) and IFN-γRβ subunits. In addition to
its antiviral effects, IFN-γ upregulates a number of lymphoid cell functions including the antimicrobial and antitumor responses of
macrophages, NK cells, and neutrophils. In addition, IFN-γ can exert strong regulatory influences on the proliferation, differentiation, and
effector responses of B cell and T cell subsets. These influences can involve IFN-γ’s capacity to boost MHC class I and II expression by
antigen-presenting cells as well as to direct effects on B cells and T cells themselves. Human IFN-γ is a 14-18 kDa glycoprotein containing
143 amino acid residues. B27 is a neutralizing antibody. The use of B27 antibody for epitope mapping of human IFN-γ has been described.
The B27 antibody has been reported not to bind to denatured IFN-γ.
Purified NA/LE Mouse Anti-Human IFN-γ Preparation and Storage：
Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.
