產(chǎn)品名稱:FITC 小鼠抗大鼠 CD4 抗體；FITC Mouse Anti-Rat CD4

中文名稱:FITC 小鼠抗大鼠 CD4 抗體

英文名稱:FITC Mouse Anti-Rat CD4

FITC Mouse Anti-Rat CD4 產(chǎn)品介紹：

Material Number: 554843
Size: 0.5 mg
Concentration: 0.5 mg/ml
Clone: OX-38
Immunogen: Rat thymocyte glycoproteins
Isotype: Mouse (BALB/c) IgG2a, κ
Reactivity: QC Testing: Rat
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

FITC Mouse Anti-Rat CD4 Description：

The OX-38 antibody has been reported to react with the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e.,
MHC class II-restricted T cells, including most T helper cells), monocytes, macrophages, and some dendritic cells. CD4 is an antigen
coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation
through its association with the T-cell receptor complex and protein tyrosine kinase lck. The OX-38 antibody has been reported to bind to the
same epitope of CD4 as that recognized by W3/25 mAb, which is a different epitope than that recognized by OX-35 mAb (Cat. No. 554837).
In vivo blocking of some cell-mediated immune responses by mAb OX-38 has been reported. Injection of OX-38 mAb induces allograft
unresponsiveness in rats, with varying results depending on the rat strain used (high or low responder). Furthermore, in vivo depletion of
CD4+ lymphocytes has been reported with this antibody.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.