產(chǎn)品名稱:FITC 小鼠抗大鼠 CD161a 抗體；FITC Mouse Anti-Rat CD161a
中文名稱:FITC 小鼠抗大鼠 CD161a 抗體
英文名稱:FITC Mouse Anti-Rat CD161a
FITC Mouse Anti-Rat CD161a 產(chǎn)品介紹：
Material Number: 555008
Alternate Name: NKR-P1A
Size: 0.5 mg
Concentration: 0.5 mg/ml
Clone: 10/78
Immunogen: Not reported
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Rat
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
FITC Mouse Anti-Rat CD161a Description：
The 10/78 antibody reacts with NKR-P1A, a 60-kDa homodimer expressed on all natural killer (NK) cells and a small subset of T
lymphocytes. The 10/78 antibody competes with the previously described 3.2.3 antibody for binding to the antigen. NKR-P1A is a type-II
integral membrane protein with an extracellular C-type lectin domain, which is an NK cell-activating receptor specific for tumor target cells.
Many rat dendritic cells have been shown to express NKR-P1A, and a subpopulation of these cells has cytotoxic activity. NKR-P1A has also
been detected at low levels on peripheral blood monocytes, and its expression is upregulated in IFN-γ-activated monocytes, specifically in a
subpopulation of large monocytes with phagocytic capacity. Furthermore, activated peripheral blood neutrophils may express a low level of
NKR-P1A. In the mouse and rat, three members of the NKR-P1 gene family have been identified; but in the human gene family, a single
NKR-P1 homologue has been discovered and designated Cd161.
FITC Mouse Anti-Rat CD161a Preparation and Storage：
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
