PE Mouse Anti-Rat CD161a
產(chǎn)品名稱: PE Mouse Anti-Rat CD161a
產(chǎn)品型號(hào): BD-555009
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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PE Mouse Anti-Rat CD161a
的詳細(xì)介紹
產(chǎn)品名稱:PE 小鼠抗大鼠 CD161a 抗體；PE Mouse Anti-Rat CD161a
中文名稱:PE 小鼠抗大鼠 CD161a 抗體
英文名稱:PE Mouse Anti-Rat CD161a
PE Mouse Anti-Rat CD161a 產(chǎn)品介紹：
Material Number: 555009
Alternate Name: NKR-P1A
Size: 0.2 mg
Concentration: 0.2 mg/ml
Clone: 10/78
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Rat
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
PE Mouse Anti-Rat CD161a Description：
The 10/78 antibody reacts with NKR-P1A, a 60-kDa homodimer expressed on all natural killer (NK) cells and a small subset of T
lymphocytes. The 10/78 antibody competes with the previously described 3.2.3 antibody for binding to the antigen. NKR-P1A is a type-II
integral membrane protein with an extracellular C-type lectin domain, which is an NK cell-activating receptor specific for tumor target cells.
Many rat dendritic cells have been shown to express NKR-P1A, and a subpopulation of these cells has cytotoxic activity. NKR-P1A has also
been detected at low levels on peripheral blood monocytes, and its expression is upregulated in IFN-γ-activated monocytes, specifically in a
subpopulation of large monocytes with phagocytic capacity. Furthermore, activated peripheral blood neutrophils may express a low level of
NKR-P1A. In the mouse and rat, three members of the NKR-P1 gene family have been identified; but in the human gene family, a single
NKR-P1 homologue has been discovered and designated Cd161.
PE Mouse Anti-Rat CD161a Preparation and Storage：
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
