PE Mouse Anti-Human CD11b/Mac-1
產(chǎn)品名稱: PE Mouse Anti-Human CD11b/Mac-1
產(chǎn)品型號(hào): BD-555388
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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PE Mouse Anti-Human CD11b/Mac-1
的詳細(xì)介紹
產(chǎn)品名稱:PE 小鼠抗人 CD11b/Mac-1 抗體;PE Mouse Anti-Human CD11b/Mac-1
中文名稱:PE 小鼠抗人 CD11b/Mac-1 抗體
英文名稱:PE Mouse Anti-Human CD11b/Mac-1
PE Mouse Anti-Human CD11b/Mac-1 產(chǎn)品介紹:
Material Number: 555388
Alternate Name: Mac-1α, integrin αM subunit, CR3 α chain
Size: 100 tests
Vol. per Test: 20 μl
Clone: ICRF44 (also known as 44)
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: IV M047
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
PE Mouse Anti-Human CD11b/Mac-1 Description:
The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18)
to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes,
and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102
(ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
PE Mouse Anti-Human CD11b/Mac-1 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.