FITC Mouse Anti-Human CD42b
產(chǎn)品名稱: FITC Mouse Anti-Human CD42b
產(chǎn)品型號: BD-555472
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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FITC Mouse Anti-Human CD42b
的詳細(xì)介紹
產(chǎn)品名稱:FITC 小鼠抗人 CD42b 抗體;FITC Mouse Anti-Human CD42b
中文名稱:FITC 小鼠抗人 CD42b 抗體
英文名稱:FITC Mouse Anti-Human CD42b
FITC Mouse Anti-Human CD42b 產(chǎn)品介紹:
Material Number: 555472
Alternate Name: GP1BA; GPIbalpha; GP-Ib alpha; GPIb-alpha; CD42b-alpha; Glycocalicin; BSS
Size: 100 tests
Vol. per Test: 20 μl
Clone: HIP1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: IV P40
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
FITC Mouse Anti-Human CD42b Description:
The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded
by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with
CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand
Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the
ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.
FITC Mouse Anti-Human CD42b Preparation and Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.