PE Mouse Anti-Human CD154
產(chǎn)品名稱: PE Mouse Anti-Human CD154
產(chǎn)品型號(hào): BD-555700
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
上海創(chuàng)賽優(yōu)勢(shì)提供PE Mouse Anti-Human CD154，BD抗體現(xiàn)貨促銷PE Mouse Anti-Human CD154，BD抗體優(yōu)惠促銷PE Mouse Anti-Human CD154，歡迎來電咨詢：400-608-7598.
PE Mouse Anti-Human CD154
的詳細(xì)介紹
產(chǎn)品名稱:PE 小鼠抗人 CD154 抗體；PE Mouse Anti-Human CD154
中文名稱:PE 小鼠抗人 CD154 抗體
英文名稱:PE Mouse Anti-Human CD154
PE Mouse Anti-Human CD154 產(chǎn)品介紹：
Material Number: 555700
Alternate Name: CD40L
Size: 100 tests
Vol. per Test: 20 μl
Clone: TRAP1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Tested in Development: Baboon, Rhesus, Cynomolgus
Workshop: VI 6T-068
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
PE Mouse Anti-Human CD154 Description：
Reacts with CD40 ligand (CD40L), a 39 kDa type II membrane glycoprotein expressed on activated T cells. CD40-CD40L interaction plays a
very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T
cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T
cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells. In addition, blocking of
CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching. It has
been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that
encodes CD40L
PE Mouse Anti-Human CD154 Preparation and Storage：
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
