FITC Mouse Anti-Human CD28
產(chǎn)品名稱: FITC Mouse Anti-Human CD28
產(chǎn)品型號: BD-555728
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
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FITC Mouse Anti-Human CD28
的詳細介紹
產(chǎn)品名稱:FITC 小鼠抗人 CD28 抗體；FITC Mouse Anti-Human CD28
中文名稱:FITC 小鼠抗人 CD28 抗體
英文名稱:FITC Mouse Anti-Human CD28
FITC Mouse Anti-Human CD28 產(chǎn)品介紹：
Material Number: 555728
Alternate Name: CD28 antigen; T44; Tp44; TP44
Size: 100 Tests
Vol. per Test: 20 μl
Clone: CD28.2
Immunogen: Human CD28 Transfected Cell Line
Isotype: Mouse (C3H x BALB/c) IgG1, κ
Reactivity: QC Testing: Human
Workshop: V 5T CD28.05
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
FITC Mouse Anti-Human CD28 Description：
The CD28.2 monoclonal antibody specifically binds to CD28, a 44 kDa homodimeric transmembrane glycoprotein present on most mature T
cells, thymocytes and plasma cells. CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in
T cell-B cell interactions. It has been suggested that CD28 initiates and regulates a separate and distinct signal transduction pathway from
those stimulated by the TCR complex. Additionally, it has been reported that CD28 antibody clones vary in their ability to stimulate T cells to
produce IL-2 and increase intracellular Ca2+ concentration. This finding suggests the existence of functionally distinct subregions on the
CD28 molecule. CD28.2 has been demonstrated to bind to the same molecule as clone L293, another CD28 mAb, and has been reported to
induce Ca2+ influx in Jurkat T cells
FITC Mouse Anti-Human CD28 Preparation and Storage：
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
