PE Mouse Anti-Human CD152
產(chǎn)品名稱: PE Mouse Anti-Human CD152
產(chǎn)品型號: BD-555853
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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PE Mouse Anti-Human CD152
的詳細(xì)介紹
產(chǎn)品名稱:PE 小鼠抗人 CD152 抗體;PE Mouse Anti-Human CD152
中文名稱:PE 小鼠抗人 CD152 抗體
英文名稱:PE Mouse Anti-Human CD152
PE Mouse Anti-Human CD152 產(chǎn)品介紹:
Material Number: 555853
Alternate Name: CTLA-4
Size: 100 tests
Vol. per Test: 20 μl
Clone: BNI3
Isotype: Mouse IgG2a, κ
Reactivity: QC Testing: Human
Workshop: NA
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
PE Mouse Anti-Human CD152 Description:
Reacts with the "cytolytic T lymphocyte-associated antigen", CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds
to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory
signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells,
suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 enhances T-cell proliferation induced by CD3
and CD28.
PE Mouse Anti-Human CD152 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.