PE Mouse Anti-Human CD221
產(chǎn)品名稱: PE Mouse Anti-Human CD221
產(chǎn)品型號(hào): BD-555999
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無(wú)相關(guān)文檔
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PE Mouse Anti-Human CD221
的詳細(xì)介紹
產(chǎn)品名稱:PE 小鼠抗人 CD221 抗體;PE Mouse Anti-Human CD221
中文名稱:PE 小鼠抗人 CD221 抗體
英文名稱:PE Mouse Anti-Human CD221
PE Mouse Anti-Human CD221 產(chǎn)品介紹:
Material Number: 555999
Alternate Name: IGF-I Receptor α
Size: 100 tests
Vol. per Test: 20 μl
Clone: 1H7
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
PE Mouse Anti-Human CD221 Description:
Reacts with human insulin-like growth factor-I (IGF-I) receptor α subunit (135 kDa). IGF-IRα is a glycoprotein complex composed of two
extracellular α subunits and two transmembrane β subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several
intracellular signaling proteins. IGF-IRα is structurally and functionally similar to insulin receptor and is expressed on a variety of human
hematopoietic and non-hematopoietic cells. It mediates the effects of IGF-I and IGF-II on cellular growth. 1H7 does not cross react with
human insulin receptor and it can block IGF-I or IGF-II stimulated cell growth.
PE Mouse Anti-Human CD221 Preparation and Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.