FITC Rat Anti-Mouse CD103
產(chǎn)品名稱: FITC Rat Anti-Mouse CD103
產(chǎn)品型號(hào): BD-557494
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無相關(guān)文檔
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FITC Rat Anti-Mouse CD103
的詳細(xì)介紹
產(chǎn)品名稱:FITC 大鼠抗小鼠 CD103 抗體；FITC Rat Anti-Mouse CD103
中文名稱:FITC 大鼠抗小鼠 CD103 抗體
英文名稱:FITC Rat Anti-Mouse CD103
FITC Rat Anti-Mouse CD103 產(chǎn)品介紹：
Material Number: 557494
Alternate Name: Integrin αIEL chain
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: M290
Immunogen: Mouse mammary tumor cells
Isotype: Rat (LOU) IgG2a, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
FITC Rat Anti-Mouse CD103 Description：
The M290 antibody reacts with the α chain of αIELβ7 integrin. CD103 has a unique and fairly restricted tissue distribution. It is expressed on
almost all intestinal intraepithelial lymphocytes (IEL), on dendritic epidermal T cells (DEC), on subpopulations of peripheral T cells, and on
distinct subsets of fetal, neonatal, and ***** thymocytes. E-cadherin is the epithelial-cell ligand for αIELβ7 integrin. The ordered expression of
αIEL during thymocyte development (which occurs under the influence of the thymic epithelium), the high level of expression of αIEL on
those peripheral T cells found in epithelial tissues (IEL and DEC), and the expression of CD103 on a subset of CD8+ lymphocytes responding
to allogeneic epithelial cells suggest that αIELβ7 integrin may have a common role in the interactions of T lymphocytes with epithelia during
T-cell maturation and effector functions. CD103 is thought to play a role in allograft rejection. The M290 antibody is reported to efficiently
inhibit αIELβ7-mediated adhesion in in vitro assays.
FITC Rat Anti-Mouse CD103 Preparation and Storage：
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
